63341 Homes for Sale

63341 Homes for Sale

Welcome to Defiance, Missouri, nestled in the picturesque St. Charles County and enveloped by the tranquil beauty of nature. The zip code 63341 is not just a number; it represents a vibrant community where charm meets convenience. Defiance is renowned for its stunning landscapes, including lush vineyards, rolling hills, and scenic views of the Missouri River, making it a perfect retreat for those seeking a serene lifestyle while still enjoying easy access to urban amenities.

Homes for sale in this enchanting area offer a diverse range of options, from quaint cottages to expansive estates, each with its unique character and charm. Whether you're a first-time homebuyer, looking to downsize, or seeking a family-friendly abode, you'll find something that suits your needs in Defiance. Many properties boast spacious yards, ideal for outdoor gatherings or simply enjoying the tranquility of the countryside.

Living in Defiance means embracing a lifestyle enriched by local wineries, outdoor recreational activities, and a strong sense of community. Residents enjoy the benefits of a relaxed pace while being just a short drive away from the bustling cities of St. Charles and St. Louis. With a growing number of amenities, including shops, restaurants, and parks, Defiance offers the perfect blend of rural charm and modern convenience.

Explore the homes for sale in the 63341 zip code and discover your dream home in this idyllic setting. Whether you’re looking to invest in a property or start a new chapter in your life, Defiance promises a warm welcome and a place to call home.

Newest 63341 Homes for Sale

$624,900
3 Beds ⋅ 3 Baths ⋅ 26057258 MLS ⋅ ACTIVE Status
Welcome to 19 Greenview Drive and to the beautiful community of Callaway Farms! This stunning home is a rare find! The style is known as an executive style reverse ranch floor plan with two levels of living. This dynamic floor plan offers numerous options for retirees, families, and for those looking for privacy with extended family. Walk in on the upper level, there is a seamless flow between the kitchen, dining area, and great room, designed for modern living and entertaining. You will love the wall of windows that overlooks the wooded back yard in the great room! Special features include: vaulted ceilings, fireplace, new windows throughout with casement windows on front (8/26), new exterior vinyl siding(8/26), gutters, roof (2025), two refinished decks (upper 27'9"x13'2") (lower 15x10'7") , oversized two car garage (27'4"x22'7") with workshop area, updated furnace (2023), water heater (8/26), updated flooring, baseboards, black door knobs, paneled closet doors, all three bathroom vanities upgraded to comfort height with granite counter tops and freshly painted a lovely neutral color! The spacious primary bedroom suite is located on the main level has a luxury en-suite with comfort height vanity, slate floor, tiled shower and spacious closet. The lower level has two bedrooms with views of the woods, full bathroom, family room with fireplace and windows over looking the wooded back yard. There are two decks off the back of the house, both were refinished and offer breath taking views. The acreage, mature trees, and secluded deck create a peaceful retreat where you can sit quietly, enjoy a cup of coffee, read a book, or simply listen to the sounds of nature. There is a wonderful sense of community without ever feeling like you have given up your privacy. The changing seasons are spectacular here. On a cold winter day, there is nothing quite like being cozy in the family room with a fire burning, watching the snow fall through the huge windows. In the fall, the trees put on a spectacular show—rows and rows of colors so beautiful that they are almost impossible to describe. Callaway Farms is more than a subdivision. It is a place where you can enjoy nature, find peace and privacy, make friends, watch the seasons change, and truly feel at home. There is something special that happens when you pull into the subdivision, connected to nature, and somehow able to breathe a little deeper. The stresses of the day seem to melt away as you exhale and leave the day's work behind. It is a peaceful, refreshing place to come home to, and if privacy is what you desire, this home offers that beautifully. Enjoy the wildlife (deer and turkey to greet you) plus the peace and tranquility of life in this quiet established neighborhood. Secluded Setting. Spacious Ranch. 3 Wooded Acres. Easy to show! Set your appointment today!

19 Greenview Dr, Defiance
$735,000
3 Beds ⋅ 4 Baths ⋅ 26055828 MLS ⋅ ACTIVE Status
Welcome to your own private retreat! Nestled on 3 beautiful acres with peaceful wooded views, this stunning 3-bedroom, 3.5-bath home offers the perfect blend of space, comfort, and entertainment. Whether you’re hosting friends for the big game, enjoying a relaxing evening surrounded by nature, or simply looking for room to spread out, this home has it all! The partially finished basement is made for entertaining, featuring a bar and a designated TV-watching space—perfect for movie nights, game days, and gatherings. Step into the enclosed seating area and enjoy your morning coffee or unwind at the end of the day while taking in the beautiful views of the woods. And with an impressive 5 garage spaces, you’ll have plenty of room for vehicles, toys, hobbies, storage, or a workshop! With 3 acres to enjoy, multiple entertaining spaces, and a peaceful setting that feels like a getaway while still offering the comforts of home, this property is one you won’t want to miss. Come see why this could be the perfect place to call home!

3840 Rooster Ridge Ln, Defiance
$675,000
3 Beds ⋅ 2 Baths ⋅ 26055317 MLS ⋅ ACTIVE Status
Dont wait ! Homes like this don't come around often in sought after area of Defiance! Rare opportunity to have a beautiful like new ranch home on 3.05 wooded acres! paved roads plus concrete driveway and Just minutes to I-64 and Hwy 94 allowing easy commutes yet peaceful country living. 11 ft ceilings and all of the natural light that fills the entertaining area. The kitchen offers tons of white cabinets, stainless farm sink, walk-in pantry, large island/breakfast bar, Quartzite Counter tops and access to huge deck with view of the peaceful, quiet setting-cozy hearth room and enjoy the warmth from the wood burning fireplace-separate dining room or office space-Primary bath has double bowl, step in shower with black onyx surround. All bedrooms have walk-in closets. Laundry/mud room is spacious and the unfinished basement walls are 9 ft, has w/i plumbing and walks out to a second deck-there is a sub basement offering additional space for a work shop, play room or flex space-Top of the line insulation throughout home-Anderson Windows-o/s rear side car garage drywalled and insulated

50 Wilderness Ln, Defiance
$650,000
3 Beds ⋅ 3 Baths ⋅ 26053053 MLS ⋅ ACTIVE Status
Tucked away on 4.75 beautiful acres surrounded by mature trees, this charming 3-bedroom, 3-bath home offers the perfect blend of privacy, space, and outdoor living. Step inside to a warm and inviting main level featuring vaulted ceilings, skylights, and natural wood accents throughout. The finished lower level provides plenty of additional living space, along with a separate finished room perfect for a home office, gym, hobby room, or other flex space. The outdoor setting is truly something special. Spend your days relaxing on the spacious back deck overlooking the above-ground pool, unwind beside the waterfall, or simply enjoy the peaceful, wooded surroundings and expansive yard. With plenty of room to entertain, play, and enjoy nature, this property offers the privacy you've been looking for. Need space for vehicles, equipment, or hobbies? The impressive detached shop/garage features two overhead doors, additional covered parking, and a large concrete drive, providing exceptional storage and workspace. From the stone-accented exterior and welcoming covered front porch to the finished lower level, outdoor entertaining spaces, pool, waterfall, acreage, and incredible shop, this property has so much to offer. This home features a new roof and septic system. If you're looking for peaceful country-style living with plenty of room inside and out, this is one you'll want to see!

85 Mar Len Dr, Defiance
$649,000
3 Beds ⋅ 2 Baths ⋅ 26053227 MLS ⋅ ACTIVE Status
Experience peaceful country living in this stunning 2- year old ranch home nestled on 5 mostly wooded, unrestricted acres in the picturesque Femme Osage Valley. Ideally located just 3.5 miles from the charming town of New Melle, you'll enjoy the perfect balance of privacy and convenience, with nearby wineries, parks, and scenic countryside. This thoughtfully designed home offers 2,013 square feet of main-level living with 3 spacious bedrooms, 2 full bathrooms, and quality finishes throughout. The open concept floor plan features soaring 10-foot ceilings, luxury vinyl plank flooring, quartz countertop, a large center island, and a stylish coffee/beverage bar that's perfect for entertaining. The primary suite and secondary bathrooms showcase beautiful custom tile work, which continues into the laundry room for a cohesive, upscale feel. Step outside to enjoy the deck overlooking the peaceful wooded acreage- an ideal setting for relaxing, entertaining, or enjoying abundant wildlife and nature. Additional highlights include an oversized 3-car garage and a full unfinished basement with a bathroom rough-in, offering endless possibilities for future expansion and added living space. Located in the highly sought after Francis Howell School District, this exceptional property combines modern luxury with the serenity of country living. Don't miss this rare opportunity to own a nearly new home on unrestricted acreage in one of St. Charles County's most desirable locations.

215 Rugged Acres, Defiance
$425,745
4 Beds ⋅ 3 Baths ⋅ 26052763 MLS ⋅ ACTIVE Status
Come and see this brand new move in ready 4 bedroom, 2.5 bath Two Story Home located in the French District. This home has Double Front Porch, Upgrade Cabinets with Island, Cambria Kitchen Countertops, Lux Vinyl Plank Flooring throughout the First Floor, Double Bowl Sink in the Master and Hall Bathrooms , Rough in plumbing in the basement, Stainless Steel Appliances with Space saver Microwave, Plus more! Price reflects Builder Discount. When you live in New Town you have access to over $10 million in amenities including parks, lakes, community waterpark, outdoor amphitheater, walkable stores, restaurants and shops!

9047 Wilkie Station St, St Charles
$559,900
4 Beds ⋅ 4 Baths ⋅ 26045108 MLS ⋅ ACTIVE Status
Escape to your own private retreat with this stunning log home nestled on 3 ACRES, where peaceful country living meets modern comfort. Surrounded by mature trees and breathtaking natural beauty, you'll enjoy the serenity of nature while remaining just 15 minutes from Highway 40 and Highway 70, offering the perfect balance of privacy and convenience. Enjoy the view from either the fully covered front deck or fully covered back deck! Inside, this spacious 4-bedroom, 3.5-bath home welcomes you with a dramatic two-story great room, soaring ceilings, a striking floor-to-ceiling stone fireplace, and an open loft overlooking the living space below. Warm bamboo flooring flows throughout the main level, complementing the rustic charm with updated finishes. The beautifully renovated kitchen is the heart of the home, featuring quartz countertops, 42-inch cabinetry, a custom tile backsplash, and updated appliances, making it as functional as it is beautiful. The thoughtfully redesigned floor plan includes a convenient main-floor laundry room, along with two bedrooms on the main level. Upstairs, you'll find a private primary suite and an additional bedroom with its own en-suite bath, offering flexible living arrangements for family or guests. This home has been meticulously maintained with significant updates, including: 2019: Extensive main-floor renovation with floor plan modifications, new hallway, added laundry room, and a completely updated kitchen. 2021: Full exterior professionally sandblasted and stained. 2022: New roof and added skylights that fill the great room with natural light. 2024: New septic system drain field and lift station, plus new garage doors. 2025: Brand-new HVAC system. Whether you're sipping coffee on the porch, enjoying evenings by the stone fireplace, or taking in the peaceful surroundings, this one-of-a-kind log home offers the lifestyle you've been dreaming of. If you've been searching for timeless character, modern updates, and room to breathe, this extraordinary property is one you won't want to miss.

8 Whippoorwill Ct, Defiance
$610,000
4 Beds ⋅ 3 Baths ⋅ 26042478 MLS ⋅ ACTIVE Status
Embrace the serenity of this secluded 3-acre property at the end of a cul-de-sac, surrounded by trees and boasting not just one, but three separate buildings! The main 2-story home features Low Maintenance, Hail resistant Hardi Board Siding, offering possible lower insurance rates. Step inside to find a ceramic tile entry, coat closet, powder room, and a grand staircase with wood rails and wrought iron balusters. The spacious L-shaped great room showcases solid oak floors and a cozy wood stove, perfect for relaxing or entertaining. The custom Real Cherry cabinets in the kitchen are complemented by upgraded Austrian hardware for soft close drawers. Oversized Primary suite with sitting room/custom make-up area/nursery. 3 bedrooms have new carpet. The property doesn't stop there - a woodworking shop or she shed, barn, and pasture offer endless possibilities for hobbies or additional living space/possible Mother-in-law quarters. The woodworking/she shed building is constructed with 2 x 6 Stud construction and over-insulated walls. The building has heat and air conditioning. Enjoy the outdoors on the back patio or covered deck, overlooking the expansive backyard. Fruit trees, black raspberry bushes, and a vegetable garden add to the charm of this peaceful retreat. With freshly painted interiors, vinyl, triple-paned insulated windows, and a partially finished lower level with a second wood stove, newley installed upgraded laminate floor, this home is move-in ready. The oversized 2-car garage provides ample storage space and room for hobbies. Located near Busch Wildlife and Weldon Spring Conservation Area, this property offers a perfect blend of privacy and convenience. Create lasting memories in this beautiful oasis - schedule a showing today!

44 Wilderness Ln, Defiance
$364,950
3 Beds ⋅ 1 Baths ⋅ 26041787 MLS ⋅ ACTIVE Status
Ranch style, full brick home situated on 4.6 acres with an attached one car garage. The home has 3 bedrooms, 1 bath, 1296 square feet, some hardwood floors, and a full basement situated on a fairly level lot. Some photos are virtually staged.

3901 Hwy D, Defiance
$505,900
3 Beds ⋅ 2 Baths ⋅ 26037883 MLS ⋅ ACTIVE Status
Spacious ranch on 6 gorgeous acres conveniently located just minutes from wineries, schools, shopping and highways! This charming 3 bedroom, 2 bath home comes complete with main floor laundry, full, unfinished basement, and a primary bedroom with walk-in closet and ensuite bath. Besides the 2-car attached garage, there is a 28’x60’ insulated metal outbuilding with concrete floor, electric and 220 AC. Lots of deer and other wildlife on the wooded acreage. Some fresh paint and flooring will make this a rural oasis while still being just minutes to town conveniences. Already reduced to be sold As-Is. Make it your own!

3877 Hwy D, Defiance
$1,400,000
5 Beds ⋅ 7 Baths ⋅ 26037028 MLS ⋅ ACTIVE Status
Stunning brick and stone ranch-style home sitting on 3 private acres surrounded by mature trees and scenic views! This custom-built home boasts 5 bedrooms, 4 full bathrooms, 3 half bathrooms, and over 6,500 square feet of living space including the finished walkout lower level. The property also features an attached 3 car garage and a detached 52 x 40 foot detached garage with a bonus room. The front door opens to the impressive entry foyer with a gallery staircase and leads to the elegant dining room and stunning great room. The great room boasts a floor-to-ceiling brick fireplace, custom millwork, a wall of windows overlooking the grounds, and French doors that open to the expansive deck. The designer kitchen features custom glazed cabinetry, granite countertops, commercial-grade appliances, a butler’s pantry, dining area with a bay window, and opens to the hearth room with a beautiful brick and stone fireplace. The light-filled sunroom provides the perfect place to relax and enjoy the picturesque setting. The luxurious main floor primary suite boasts a brick fireplace, private sitting area, deck access, walk-in closets, and a spa-like bathroom with a jetted tub, separate shower, and dual vanities. The stylish powder room and laundry room complete the main level. The finished walkout lower level is designed for entertaining and features a spacious recreation room with a stone fireplace, wet bar, office, workout room, guest suite, two additional bedrooms connected by a Jack and Jill bathroom, and a half bathroom. The lower level also features ample storage space. Other highlights include: extensive custom millwork, coffered ceilings, professional landscaping, multiple waterfalls, newer hardwood floors on the main level, and painted neutral colors throughout most of the home. Relax outside on the expansive deck overlooking the scenic grounds, enjoy the beautifully landscaped yard with waterfalls. Location could not be better – close to major highways, restaurants, shops, parks, hiking trails, wineries, and Francis Howell schools!

220 Northlind Dr, Defiance
$649,900
4 Beds ⋅ 3 Baths ⋅ 26030764 MLS ⋅ ACTIVE Status
Nestled on 8+ scenic acres off coveted Matson Hill Road in Unincorporated St. Charles County, this meticulously maintained retreat offers the perfect blend of refined comfort and peaceful country living. Surrounded by mature trees, wildlife, and nature, this stunning property delivers privacy without sacrificing convenience. Welcoming foyer opens to formal living and dining rooms before leading to a breathtaking vaulted and beamed great room anchored by a wood-burning fireplace. Spacious country kitchen features custom wood cabinetry, Corian countertops, center island, double ovens, and breakfast area that opens to an expansive approx. 36’x20’ deck with tempered glass railing designed to maximize views of the surrounding woods and wildlife. Enjoy deer, turkey, birds, and a private wooded path leading to a wet-weather creek. Upper level offers 3 spacious bedrooms with hardwood flooring throughout. Luxurious owner’s suite includes walk-in closet and updated bath with marble tops, adult-height double vanities, and tiled shower. Finished walk-out lower level is ideal for multi-generational living or guest quarters with sleeping area, den, kitchenette, and full bath. Oversized side-entry garage offers RV hookup, generator hookup, workshop space, and abundant storage. Circular driveway welcomes guests while additional drive leads to pole barn with electric and lean-to for equipment, hobbies, workshop, or storage. Minutes from Matson Hill Park, the Katy Trail, wineries, and all the beauty Defiance area living has to offer.

800 Matson Hill Rd, Defiance
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