Defiance Homes for Sale

Defiance Homes for Sale

Welcome to Defiance, Missouri—a hidden gem nestled in the heart of St. Charles County. This charming town, with its picturesque landscapes and a close-knit community, offers a perfect blend of rural tranquility and modern conveniences. Just a stone's throw from the bustling city of St. Louis, Defiance provides residents with easy access to urban amenities while maintaining the serene lifestyle of a small town.

Defiance is renowned for its stunning natural beauty, with rolling hills, lush vineyards, and the scenic Missouri River flowing nearby. Outdoor enthusiasts will find plenty to love, from hiking and biking trails to local parks that invite picnics and family gatherings. The town's rich history is reflected in its quaint architecture and friendly atmosphere, making it an inviting place for families, retirees, and everyone in between.

For those considering a move to this enchanting area, you’ll be delighted to discover a variety of homes for sale that cater to diverse tastes and budgets. Whether you’re looking for a cozy cottage, a spacious family home, or a luxurious estate with breathtaking views, Defiance has something for everyone. Many properties boast expansive yards, perfect for gardening or entertaining, and some even feature proximity to local vineyards, making it easy to enjoy the region's renowned wine culture.

Embrace the charm of Defiance, where community spirit thrives and homes are more than just houses—they're a place to create lasting memories. Explore the current listings today and take the first step toward making this delightful town your new home!

Newest Defiance Homes for Sale

$624,900
3 Beds ⋅ 3 Baths ⋅ 26057258 MLS ⋅ ACTIVE Status
Welcome to 19 Greenview Drive and to the beautiful community of Callaway Farms! This stunning home is a rare find! The style is known as an executive style reverse ranch floor plan with two levels of living. This dynamic floor plan offers numerous options for retirees, families, and for those looking for privacy with extended family. Walk in on the upper level, there is a seamless flow between the kitchen, dining area, and great room, designed for modern living and entertaining. You will love the wall of windows that overlooks the wooded back yard in the great room! Special features include: vaulted ceilings, fireplace, new windows throughout with casement windows on front (8/26), new exterior vinyl siding(8/26), gutters, roof (2025), two refinished decks (upper 27'9"x13'2") (lower 15x10'7") , oversized two car garage (27'4"x22'7") with workshop area, updated furnace (2023), water heater (8/26), updated flooring, baseboards, black door knobs, paneled closet doors, all three bathroom vanities upgraded to comfort height with granite counter tops and freshly painted a lovely neutral color! The spacious primary bedroom suite is located on the main level has a luxury en-suite with comfort height vanity, slate floor, tiled shower and spacious closet. The lower level has two bedrooms with views of the woods, full bathroom, family room with fireplace and windows over looking the wooded back yard. There are two decks off the back of the house, both were refinished and offer breath taking views. The acreage, mature trees, and secluded deck create a peaceful retreat where you can sit quietly, enjoy a cup of coffee, read a book, or simply listen to the sounds of nature. There is a wonderful sense of community without ever feeling like you have given up your privacy. The changing seasons are spectacular here. On a cold winter day, there is nothing quite like being cozy in the family room with a fire burning, watching the snow fall through the huge windows. In the fall, the trees put on a spectacular show—rows and rows of colors so beautiful that they are almost impossible to describe. Callaway Farms is more than a subdivision. It is a place where you can enjoy nature, find peace and privacy, make friends, watch the seasons change, and truly feel at home. There is something special that happens when you pull into the subdivision, connected to nature, and somehow able to breathe a little deeper. The stresses of the day seem to melt away as you exhale and leave the day's work behind. It is a peaceful, refreshing place to come home to, and if privacy is what you desire, this home offers that beautifully. Enjoy the wildlife (deer and turkey to greet you) plus the peace and tranquility of life in this quiet established neighborhood. Secluded Setting. Spacious Ranch. 3 Wooded Acres. Easy to show! Set your appointment today!

19 Greenview Dr, Defiance
$735,000
3 Beds ⋅ 4 Baths ⋅ 26055828 MLS ⋅ ACTIVE Status
Welcome to your own private retreat! Nestled on 3 beautiful acres with peaceful wooded views, this stunning 3-bedroom, 3.5-bath home offers the perfect blend of space, comfort, and entertainment. Whether you’re hosting friends for the big game, enjoying a relaxing evening surrounded by nature, or simply looking for room to spread out, this home has it all! The partially finished basement is made for entertaining, featuring a bar and a designated TV-watching space—perfect for movie nights, game days, and gatherings. Step into the enclosed seating area and enjoy your morning coffee or unwind at the end of the day while taking in the beautiful views of the woods. And with an impressive 5 garage spaces, you’ll have plenty of room for vehicles, toys, hobbies, storage, or a workshop! With 3 acres to enjoy, multiple entertaining spaces, and a peaceful setting that feels like a getaway while still offering the comforts of home, this property is one you won’t want to miss. Come see why this could be the perfect place to call home!

3840 Rooster Ridge Ln, Defiance
$675,000
3 Beds ⋅ 2 Baths ⋅ 26055317 MLS ⋅ ACTIVE Status
Dont wait ! Homes like this don't come around often in sought after area of Defiance! Rare opportunity to have a beautiful like new ranch home on 3.05 wooded acres! paved roads plus concrete driveway and Just minutes to I-64 and Hwy 94 allowing easy commutes yet peaceful country living. 11 ft ceilings and all of the natural light that fills the entertaining area. The kitchen offers tons of white cabinets, stainless farm sink, walk-in pantry, large island/breakfast bar, Quartzite Counter tops and access to huge deck with view of the peaceful, quiet setting-cozy hearth room and enjoy the warmth from the wood burning fireplace-separate dining room or office space-Primary bath has double bowl, step in shower with black onyx surround. All bedrooms have walk-in closets. Laundry/mud room is spacious and the unfinished basement walls are 9 ft, has w/i plumbing and walks out to a second deck-there is a sub basement offering additional space for a work shop, play room or flex space-Top of the line insulation throughout home-Anderson Windows-o/s rear side car garage drywalled and insulated

50 Wilderness Ln, Defiance
$650,000
3 Beds ⋅ 3 Baths ⋅ 26053053 MLS ⋅ ACTIVE Status
Tucked away on 4.75 beautiful acres surrounded by mature trees, this charming 3-bedroom, 3-bath home offers the perfect blend of privacy, space, and outdoor living. Step inside to a warm and inviting main level featuring vaulted ceilings, skylights, and natural wood accents throughout. The finished lower level provides plenty of additional living space, along with a separate finished room perfect for a home office, gym, hobby room, or other flex space. The outdoor setting is truly something special. Spend your days relaxing on the spacious back deck overlooking the above-ground pool, unwind beside the waterfall, or simply enjoy the peaceful, wooded surroundings and expansive yard. With plenty of room to entertain, play, and enjoy nature, this property offers the privacy you've been looking for. Need space for vehicles, equipment, or hobbies? The impressive detached shop/garage features two overhead doors, additional covered parking, and a large concrete drive, providing exceptional storage and workspace. From the stone-accented exterior and welcoming covered front porch to the finished lower level, outdoor entertaining spaces, pool, waterfall, acreage, and incredible shop, this property has so much to offer. This home features a new roof and septic system. If you're looking for peaceful country-style living with plenty of room inside and out, this is one you'll want to see!

85 Mar Len Dr, Defiance
$649,000
3 Beds ⋅ 2 Baths ⋅ 26053227 MLS ⋅ ACTIVE Status
Experience peaceful country living in this stunning 2- year old ranch home nestled on 5 mostly wooded, unrestricted acres in the picturesque Femme Osage Valley. Ideally located just 3.5 miles from the charming town of New Melle, you'll enjoy the perfect balance of privacy and convenience, with nearby wineries, parks, and scenic countryside. This thoughtfully designed home offers 2,013 square feet of main-level living with 3 spacious bedrooms, 2 full bathrooms, and quality finishes throughout. The open concept floor plan features soaring 10-foot ceilings, luxury vinyl plank flooring, quartz countertop, a large center island, and a stylish coffee/beverage bar that's perfect for entertaining. The primary suite and secondary bathrooms showcase beautiful custom tile work, which continues into the laundry room for a cohesive, upscale feel. Step outside to enjoy the deck overlooking the peaceful wooded acreage- an ideal setting for relaxing, entertaining, or enjoying abundant wildlife and nature. Additional highlights include an oversized 3-car garage and a full unfinished basement with a bathroom rough-in, offering endless possibilities for future expansion and added living space. Located in the highly sought after Francis Howell School District, this exceptional property combines modern luxury with the serenity of country living. Don't miss this rare opportunity to own a nearly new home on unrestricted acreage in one of St. Charles County's most desirable locations.

215 Rugged Acres, Defiance
$559,900
4 Beds ⋅ 4 Baths ⋅ 26045108 MLS ⋅ ACTIVE Status
Escape to your own private retreat with this stunning log home nestled on 3 ACRES, where peaceful country living meets modern comfort. Surrounded by mature trees and breathtaking natural beauty, you'll enjoy the serenity of nature while remaining just 15 minutes from Highway 40 and Highway 70, offering the perfect balance of privacy and convenience. Enjoy the view from either the fully covered front deck or fully covered back deck! Inside, this spacious 4-bedroom, 3.5-bath home welcomes you with a dramatic two-story great room, soaring ceilings, a striking floor-to-ceiling stone fireplace, and an open loft overlooking the living space below. Warm bamboo flooring flows throughout the main level, complementing the rustic charm with updated finishes. The beautifully renovated kitchen is the heart of the home, featuring quartz countertops, 42-inch cabinetry, a custom tile backsplash, and updated appliances, making it as functional as it is beautiful. The thoughtfully redesigned floor plan includes a convenient main-floor laundry room, along with two bedrooms on the main level. Upstairs, you'll find a private primary suite and an additional bedroom with its own en-suite bath, offering flexible living arrangements for family or guests. This home has been meticulously maintained with significant updates, including: 2019: Extensive main-floor renovation with floor plan modifications, new hallway, added laundry room, and a completely updated kitchen. 2021: Full exterior professionally sandblasted and stained. 2022: New roof and added skylights that fill the great room with natural light. 2024: New septic system drain field and lift station, plus new garage doors. 2025: Brand-new HVAC system. Whether you're sipping coffee on the porch, enjoying evenings by the stone fireplace, or taking in the peaceful surroundings, this one-of-a-kind log home offers the lifestyle you've been dreaming of. If you've been searching for timeless character, modern updates, and room to breathe, this extraordinary property is one you won't want to miss.

8 Whippoorwill Ct, Defiance
$610,000
4 Beds ⋅ 3 Baths ⋅ 26042478 MLS ⋅ ACTIVE Status
Embrace the serenity of this secluded 3-acre property at the end of a cul-de-sac, surrounded by trees and boasting not just one, but three separate buildings! The main 2-story home features Low Maintenance, Hail resistant Hardi Board Siding, offering possible lower insurance rates. Step inside to find a ceramic tile entry, coat closet, powder room, and a grand staircase with wood rails and wrought iron balusters. The spacious L-shaped great room showcases solid oak floors and a cozy wood stove, perfect for relaxing or entertaining. The custom Real Cherry cabinets in the kitchen are complemented by upgraded Austrian hardware for soft close drawers. Oversized Primary suite with sitting room/custom make-up area/nursery. 3 bedrooms have new carpet. The property doesn't stop there - a woodworking shop or she shed, barn, and pasture offer endless possibilities for hobbies or additional living space/possible Mother-in-law quarters. The woodworking/she shed building is constructed with 2 x 6 Stud construction and over-insulated walls. The building has heat and air conditioning. Enjoy the outdoors on the back patio or covered deck, overlooking the expansive backyard. Fruit trees, black raspberry bushes, and a vegetable garden add to the charm of this peaceful retreat. With freshly painted interiors, vinyl, triple-paned insulated windows, and a partially finished lower level with a second wood stove, newley installed upgraded laminate floor, this home is move-in ready. The oversized 2-car garage provides ample storage space and room for hobbies. Located near Busch Wildlife and Weldon Spring Conservation Area, this property offers a perfect blend of privacy and convenience. Create lasting memories in this beautiful oasis - schedule a showing today!

44 Wilderness Ln, Defiance
$364,950
3 Beds ⋅ 1 Baths ⋅ 26041787 MLS ⋅ ACTIVE Status
Ranch style, full brick home situated on 4.6 acres with an attached one car garage. The home has 3 bedrooms, 1 bath, 1296 square feet, some hardwood floors, and a full basement situated on a fairly level lot. Some photos are virtually staged.

3901 Hwy D, Defiance
$505,900
3 Beds ⋅ 2 Baths ⋅ 26037883 MLS ⋅ ACTIVE Status
Spacious ranch on 6 gorgeous acres conveniently located just minutes from wineries, schools, shopping and highways! This charming 3 bedroom, 2 bath home comes complete with main floor laundry, full, unfinished basement, and a primary bedroom with walk-in closet and ensuite bath. Besides the 2-car attached garage, there is a 28’x60’ insulated metal outbuilding with concrete floor, electric and 220 AC. Lots of deer and other wildlife on the wooded acreage. Some fresh paint and flooring will make this a rural oasis while still being just minutes to town conveniences. Already reduced to be sold As-Is. Make it your own!

3877 Hwy D, Defiance
$1,400,000
5 Beds ⋅ 7 Baths ⋅ 26037028 MLS ⋅ ACTIVE Status
Stunning brick and stone ranch-style home sitting on 3 private acres surrounded by mature trees and scenic views! This custom-built home boasts 5 bedrooms, 4 full bathrooms, 3 half bathrooms, and over 6,500 square feet of living space including the finished walkout lower level. The property also features an attached 3 car garage and a detached 52 x 40 foot detached garage with a bonus room. The front door opens to the impressive entry foyer with a gallery staircase and leads to the elegant dining room and stunning great room. The great room boasts a floor-to-ceiling brick fireplace, custom millwork, a wall of windows overlooking the grounds, and French doors that open to the expansive deck. The designer kitchen features custom glazed cabinetry, granite countertops, commercial-grade appliances, a butler’s pantry, dining area with a bay window, and opens to the hearth room with a beautiful brick and stone fireplace. The light-filled sunroom provides the perfect place to relax and enjoy the picturesque setting. The luxurious main floor primary suite boasts a brick fireplace, private sitting area, deck access, walk-in closets, and a spa-like bathroom with a jetted tub, separate shower, and dual vanities. The stylish powder room and laundry room complete the main level. The finished walkout lower level is designed for entertaining and features a spacious recreation room with a stone fireplace, wet bar, office, workout room, guest suite, two additional bedrooms connected by a Jack and Jill bathroom, and a half bathroom. The lower level also features ample storage space. Other highlights include: extensive custom millwork, coffered ceilings, professional landscaping, multiple waterfalls, newer hardwood floors on the main level, and painted neutral colors throughout most of the home. Relax outside on the expansive deck overlooking the scenic grounds, enjoy the beautifully landscaped yard with waterfalls. Location could not be better – close to major highways, restaurants, shops, parks, hiking trails, wineries, and Francis Howell schools!

220 Northlind Dr, Defiance
$649,900
4 Beds ⋅ 3 Baths ⋅ 26030764 MLS ⋅ ACTIVE Status
Nestled on 8+ scenic acres off coveted Matson Hill Road in Unincorporated St. Charles County, this meticulously maintained retreat offers the perfect blend of refined comfort and peaceful country living. Surrounded by mature trees, wildlife, and nature, this stunning property delivers privacy without sacrificing convenience. Welcoming foyer opens to formal living and dining rooms before leading to a breathtaking vaulted and beamed great room anchored by a wood-burning fireplace. Spacious country kitchen features custom wood cabinetry, Corian countertops, center island, double ovens, and breakfast area that opens to an expansive approx. 36’x20’ deck with tempered glass railing designed to maximize views of the surrounding woods and wildlife. Enjoy deer, turkey, birds, and a private wooded path leading to a wet-weather creek. Upper level offers 3 spacious bedrooms with hardwood flooring throughout. Luxurious owner’s suite includes walk-in closet and updated bath with marble tops, adult-height double vanities, and tiled shower. Finished walk-out lower level is ideal for multi-generational living or guest quarters with sleeping area, den, kitchenette, and full bath. Oversized side-entry garage offers RV hookup, generator hookup, workshop space, and abundant storage. Circular driveway welcomes guests while additional drive leads to pole barn with electric and lean-to for equipment, hobbies, workshop, or storage. Minutes from Matson Hill Park, the Katy Trail, wineries, and all the beauty Defiance area living has to offer.

800 Matson Hill Rd, Defiance
$695,000
3 Beds ⋅ 3 Baths ⋅ 26023721 MLS ⋅ ACTIVE Status
Welcome to your dream home - a stunning, cozy, country home nestled in the middle of the woods on 3 acres. The newest addition is the August, 2026 upgraded, county approved septic system. This home is an oasis located in St. Charles County wine country, minutes from some of St. Charles ’best hiking & biking trails! This outdoor play scape was designed with the outdoors lover in mind and has ample green-space to enjoy. This remarkable property features an inviting inground HEATED Gunite pool complete with a fun slide and beautiful cabana equipped with a wood burning stone fireplace, refrigerator and TV - ideal for relaxing or entertaining friends and family year-round. You & your family could be swimming now! Step inside to discover a comfortable 3-bedroom, 2.5 bath residence designed for modern living. The open-concept kitchen is the heart of the home and showcases custom, Thomasville soft-close cabinetry with pull-outs, under-cabinet lights, quartz countertops, granite sinks, stone backsplash, stainless steel appliances with a double-oven range and ample workspace. The kitchen has two pantries, a wet bar with a beverage refrigerator, and beautiful glass front cabinets. Enjoy casual dining at the breakfast bar or more formal dining in the spacious, adjacent dining room which opens to the beautiful covered front porch. The family room is truly stunning, highlighted by authentic barn wood accent walls, a rustic stone, vent-free, gas fireplace and direct access to the deck and pool area - creating another inviting space for relaxation and entertainment. The main level boasts a spacious primary suite with access to both a half bath and a full bath, along with a private entry to a fabulous sunroom that connects to both the covered front porch and private side deck. The sunroom has all Pella windows with inside window shades and offers all season, year-round comfort. Laundry is conveniently located on the main floor. Upstairs you will find two spacious bedrooms with a large, full bath, providing comfortable accommodations for family or guests. The partially finished walk-out lower level is perfect for gatherings, featuring another wet bar, a beautiful stone, vent-free gas fireplace, and luxury COREtec vinyl plank flooring. Step outside the French doors to a peaceful covered patio. Outdoor amenities abound with a two-car detached garage/workshop, storage shed, and a versatile two-car carport. The grounds are breathtaking, enhanced by professional landscaping and an irrigation system for easy maintenance with no water bill. Exterior updates include new roof, siding and gutters in 2024 and a new composite deck installed in 2025. You will enjoy the peace and privacy of a serene country road shared with just 2 other homes, yet benefit from a close-in location which puts shopping and dining within easy reach. The best days at 51 Nordic Lane are rainy ones as you relax on the large covered front porch or under cover of the pool cabana! If you love the outdoors and are looking for a perfect combination of tranquility, comfort and convenience, this exceptional home delivers on every level.

51 Nordic Ln, Defiance
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